- Eagleville
- Earl Township
- Earlington
- Earlville
- East Allen
- East Berlin
- East Brady
- East Conemaugh
- East Freedom
- East Greenville
- East Norriton
- East Petersburg
- East Stroudsburg
- East Texas
- East Union
- East Waterford
- Easton
- Ebensburg
- Edinboro
- Effort
- Eldred
- Eldred Township
- Elizabeth
- Elizabethtown
- Elizabethville
- Elkins Park
- Elliottsburg
- Ellwood City
- Elmhurst
- Elmhurst Township
- Elmora
- Elverson
- Elysburg
- Emerald Lakes
- Emigsville
- Emmaus
- Enola
- Entriken
- Ephrata
- Erie
- Ernest
- Erwinna
- Essington
- Etters
- Everett
- Exton